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This gene is a member with the SUMO gene relatives. This family of genes encode compact ubiquitin-similar modifiers which might be hooked up to proteins and Handle the focus on proteins' here subcellular localization, stability, or exercise. The protein explained In this particular report is located inside the cytoplasm and exclusively modifies IKBA, bringing about destructive regulation of NF-kappa-B-dependent transcription of the IL12B gene.
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